Patents & Licenses

Many BDSC stocks contain patented components. Some are listed below, but this list is not exhaustive. Most patent owners permit unrestricted use of their materials for nonprofit research only but some require licenses for any use. We provide notification of licensing requirements when stipulated by distribution agreements, but lack of notification should not be construed as a lack of licensing requirements for for-profit research. It is the recipient's responsibility to obtain any necessary licenses from the patent holder for commercial work with these stocks.

We provide contact information for recipients of specific stocks with patented components to patent holders only upon prior arrangement and only when recipients are notified of the licensing requirement during the ordering process. Otherwise, ordering information is confidential and we will share it only if we are compelled by legal actions.

The U.S. Patent and Trademark Office (PTO) offers a searchable full-text database of U.S. patents issued since January 1, 1976. Google's patent search includes patents from the U.S. and many non-U.S. countries plus documents from the Prior Arts Archive. FlyBase also includes some Drosophila patent citations in its references.

Report of the National Institutes of Health (NIH) Working Group on Research Tools

Patents and Licenses of Particular Relevance to Drosophila Researchers

  • United States Patent Number 11366114 Genetically encoded fluorescent sensors for detecting ligand bias and intracellular signaling through cAMP pathways
  • European Patent Number EP3065754B1Genetically encoded fluorescent sensors for detecting ligand bias and intracellular signaling through cAMP pathways

United States Patent Number 8697359  CRISPR-Cas systems and methods for altering expression of gene products

  • Any use of Exelixis, Inc. stocks for commercial research requires a separate use license.  Please visit this page for licensing information.

  • United States Patent Number 5491084 Uses of green-fluorescent protein
  • United States Patent Number 5541309 Modified apoaequorin having increased bioluminescent activity
  • United States Patent Number 5804387 FACS-optimized mutants of the green fluorescent protein

United States Patent Application Number  20110111445  Peptide for determining actin structures in living cells

United States Patent Numbers 5348874, 6159717, and 6469228 Eukaryotic transposable element

United States Patent Number 5840865 Eukaryotic transposable element has expired.

These original piggyBac patents have expired:

  • United States Patent Number 7105343 Methods and compositions for transposition using minimal segments of the eukaryotic transformation vector piggyBac
  • United States Patent Number 7129083 piggyBac transformation system

However, this patent is still valid:

  • United States Patent Number US11186847 Minimal piggyBac vectors for genome integration

United States Patent Number 6124128 Long wavelength engineered fluorescent proteins

Expired Patents of Particular Relevance to Drosophila Researchers

  • United States Patent Number 4959317 Site-specific recombination of DNA in eukaryotic cells
  • Memorandum of Understanding between Dupont and the PHS

United States Patent Number 5641673 Cell ablation using trans-splicing ribozymes

United States Patent Number 4670388 Method of incorporating DNA into genome of Drosophila