|We solicit stocks in the following categories that provide either new or improved material:
- Stocks that represent genetic tools of use to a broad range of research
projects, such as deficiencies and duplications, improved balancers, good
dominant markers, mapping stocks, stocks for mutagenesis, GAL4/UAS and other
stocks for directed gene expression, FLP/FRT and other stocks for clonal
analysis, and tissue-marking GFP or lacZ reporter lines.
- Well characterized
mutations affecting known structures, organs, or processes, e.g., cell division,
early development, the visual system, development or function of the nervous
system, and metabolism.
- One or two insertion alleles of annotated genes that are not already represented in the collection
by characterized mutations.
- One or two alleles of mapped but otherwise uncharacterized
visible, lethal, or sterile complementation groups from saturation screens.
- Special purpose strains
that are not easily regenerated, such as certain chromosomal aberrations
and marker combinations. All stocks added to the collection must be available
for distribution to any researcher for any purpose, be reasonably healthy
and be stable without selection.
|Stocks are removed
from the collection when a critical component is found to be not-as-represented
or when a stock is deemed redundant or no longer of sufficient value to
warrant space in the collection (sometimes due to new information about
stock components, but usually due to changing techniques employed by fly
workers). There are four categories of redundancy:
- Stocks with small
genotypic differences, such as the same aberration with different markers,
that are not heavily used.
- Multiple alleles with similar characteristics
or undetermined characteristics.
- Transgenic insertions in regions with
good representation by more useful insertions.
- Stocks whose primary purpose
is now better served by another stock, or can be equally well served by
a more versatile stock.
contact Kevin Cook or Annette Parks if you have stocks that you would like to contribute to